On Tue, 3 Jun 2014, Henrique Andrade wrote: The general answer is, please experiment and tell us what you find. But I'll venture a few comments. Maybe. The big potential speed-up would be using the gretl gdtb (binary) format, but this applies only for big datasets. Depends on hardware and software of which I have no knowledge. Maybe. In principle yes, I think that should give a speed-up. Whether it's noticeable, I don't know. I doubt whether that would be noticeable; but it would be interesting to know. Not sure what you mean there. Both gretl matrices and gretl series are pretty "light" in memory usage; neither of them require much more than (number of numerical values) times (size of double-precision floating point value). Allin Cottrell